Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

A recent review identifies interleukin-36 (IL-36) as a transformative driver of vascular inflammation, revealing that serum ...

Growing neurons rely on chemical cues to find their targets, but new research shows that the brain’s physical properties help ...

Molecularly targeted therapies are increasingly relevant in clinical oncology, as they enable the selective modulation of specific biologic targets—such as enzymes or receptors—by inhibiting or ...

On the occasion of Rare Disease Day, the Biofisika Institute (CSIC, EHU) presents the progress of a project aimed at understanding the molecular origin of CTNNB1 neurodevelopmental syndrome, a rare ...

Under states of cellular stress or inflammatory signaling, investigations indicate that IRR expression may increase, allowing selective ligands such as ARA-290 to initiate downstream signaling.