A recent review identifies interleukin-36 (IL-36) as a transformative driver of vascular inflammation, revealing that serum concentrations in patients with coronary artery disease (CAD) are ...

Growing neurons rely on chemical cues to find their targets, but new research shows that the brain’s physical properties help ...

Molecularly targeted therapies are increasingly relevant in clinical oncology, as they enable the selective modulation of specific biologic targets—such as enzymes or receptors—by inhibiting or ...

On the occasion of Rare Disease Day, the Biofisika Institute (CSIC, EHU) presents the progress of a project aimed at understanding the molecular origin of CTNNB1 neurodevelopmental syndrome, a rare ...

Under states of cellular stress or inflammatory signaling, investigations indicate that IRR expression may increase, allowing selective ligands such as ARA-290 to initiate downstream signaling.

Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more effectively. The new approach could be a way to deliver treatment directly to tumors ...

Perovskite solar cells (PSCs) are known for their impressive ability to convert sunlight into energy, their low production costs and their lightweight design. They may well be the rising stars of ...

Perovskite solar cells have long been the most exciting “almost there” technology in clean energy. In laboratories, they already rival the best silicon solar cells, converting more than 26 percent of ...

A research team from Osaka Metropolitan University have developed a donor-acceptor-donor molecule that can spontaneously self-assemble into nanoscale structures and offer a more stable route to ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Chronic kidney disease (CKD) is a progressive condition in which the kidneys gradually lose their ability to filter waste from the blood. It is a common health concern that affects an estimated 8–16% ...

CCL5 protects podocytes, the kidney’s essential filtration cells, but simultaneously drives harmful inflammation. Ultimately, these damaging effects surpass its protective role, leading to progressive ...