Growing neurons rely on chemical cues to find their targets, but new research shows that the brain’s physical properties help ...

The brain's hardware and software are not separate. A new study reveals that the physical stiffness of brain tissue directly dictates which chemical signals neurons receive, a finding that upends ...

This insight may also help researchers better understand how other organs develop and could eventually inspire new medical ...

New UAB research uncovers how NFAT helps uterine NK cells support early placenta development, shedding light on pregnancy health and the roots of complications like preeclampsia.

Rather than aligning with classical hematopoietic signaling, the peptide has been theorized to engage selective molecular pathways associated with cellular stress response, immunomodulatory signaling, ...

As the Arctic region becomes increasingly contested, the U.S. military faces a new era of challenges in one of the world's most inhospitable environments. Researchers at the Johns Hopkins Applied ...

Magnetoelectric nanoparticles embedded in a hydrogel and delivered by a threaded acupuncture needle activate mast cells under ...

Adhesion GPCRs are a large class of surface proteins that recognize chemical and mechanical stimuli in the body. The rapidly expanding body of knowledge on the therapeutic targeting of these receptors ...

GSK-J4（AbMole，M5149）是一种特异性抑制组蛋白H3K27me3去甲基化酶的小分子化合物，其作用机制主要通过调控表观遗传修饰影响下游的信号通路。在细胞实验中，GSK-J4对多种肿瘤细胞系表现出显著的增殖抑制作用：在视网膜母细胞瘤中，1- ...

Molecularly targeted therapies are increasingly relevant in clinical oncology, as they enable the selective modulation of specific biologic targets—such as enzymes or receptors—by inhibiting or ...

Dr Samrat Basak mastering the new generation of microfluidics system; Kim-Chi Vu in process of preparation of specialized muscle cells of the heart; Dr Roman Tsukanov in the optical/microfluidics lab.