It turns out that not all the hairlike cilia projecting from the surfaces of many cells in the human body are equal—there are the myriad ones for sweeping, swimming and other functions, and then there ...

STANFORD, Calif. — Nearly all mammalian cells have what's called a primary cilium — a single, stump-like rod projecting from the smooth contours of the cell's outer membrane. Unlike its more ...

Researchers have pinpointed the molecular cause of a rare genetic disease in humans called Bardet-Biedl syndrome, or BBS. People with the disorder suffer from obesity, retinal degeneration, kidney ...

Autophagy is a degradative and recycling mechanism that allows cells to adapt to stress situations including nutrient deprivation. Primary cilia (PC) and motile cilia (MC) are sensory structures at ...

Genetic causes of obesity include the ciliopathies Alström syndrome and Bardet–Biedl syndrome. In these disorders, mutations cause dysfunction of the primary cilium, an organelle involved in ...

Sanja Sviben and Alexander Polino, Washington University in St. Louis. In her lab at Washington University in St. Louis, endocrinologist Jing Hughes studies a peculiar structure that sticks out of the ...