It turns out that not all the hairlike cilia projecting from the surfaces of many cells in the human body are equal—there are the myriad ones for sweeping, swimming and other functions, and then there ...

Researchers have pinpointed the molecular cause of a rare genetic disease in humans called Bardet-Biedl syndrome, or BBS. People with the disorder suffer from obesity, retinal degeneration, kidney ...

Genetic causes of obesity include the ciliopathies Alström syndrome and Bardet–Biedl syndrome. In these disorders, mutations cause dysfunction of the primary cilium, an organelle involved in ...

Sanja Sviben and Alexander Polino, Washington University in St. Louis. In her lab at Washington University in St. Louis, endocrinologist Jing Hughes studies a peculiar structure that sticks out of the ...

Dutch researchers have found a new gene for Sensenbrenner syndrome. The mutation adds support to the hypothesis that defects in ciliar transport are the cause of the disease. Dutch researchers of the ...

STANFORD, Calif. — Nearly all mammalian cells have what's called a primary cilium — a single, stump-like rod projecting from the smooth contours of the cell's outer membrane. Unlike its more ...