Here, we investigated the complement binding of necrotic and apoptotic cells in different states of cell death. To induce necrosis of polymorphonuclear cells (PMN) and of peripheral blood lymphocytes ...

The fact that the complement system is activated during immune-complex glomerular disease has been known for nearly 50 years. Detection of complement deposition in the glomerulus using immunochemistry ...

The complement community is shifting gear, with more companies than ever targeting alternative complement proteins for their therapies, allowing for a larger range of diseases to be targeted. With ...