The Diels-Alder reaction is a classic transformation that typically marries a diene (with four π electrons) and an alkene (with two π electrons) to form a six-membered ring—it’s known as a [4+2] ...

Multicomponent reactions allow for more bond-forming events per synthetic operation, enabling more step- and time-economical conversion of simple starting materials to complex and thus value-added ...

The use of 1-hydrazinodienes in the Diels-Alder reaction is adding a new twist to the well-studied reaction: The cycloaddition product may be driven to rearrange, according to research by Princeton ...

The Diels-Alder reaction is the most iconic organic chemistry reaction. Scientists now report on exactly how this chemical reaction, discovered in 1928, occurs. In 1928, chemists Otto Diels and Kurt ...

Maleic anhydride is perhaps best known as the quintessential dienophile in the Diels–Alder cycloaddition reaction, but it is also used as a ligand in metal complexes and as a feedstock for maleic acid ...