A cell model that replicates the structure and function of the human intestine has been developed, creating an evaluation platform capable of more accurately predicting adverse effects of new drugs.

Many people believe that memory loss is simply a normal part of getting older. It is common to hear that aging automatically leads to forgetfulness and slower thinking. However, this is not always ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

Experiments using mouse models revealed that aging alters the balance of commensal (or helpful) microbes in the gut. These ...

Scientists at MIT have discovered that a little-known protein called intelectin-2 plays a powerful double role in defending the gut. The protein strengthens the mucus layer that lines the ...

Methods developed and validated to establish the "World Bank of NK Cells" from healthy donors and cancer patients -- Single apheresis yields up to 5 billion (5×109) highly pure activated memory ...

Over time, the constant inflammation can damage the lining of the intestine and lead to other health problems. One of the most serious complications is a higher risk of developing colorectal cancer, ...

Akkermansia is described as a bacterium that fortifies a person's gut lining, reduces gut permeability, and supports metabolic function.

Our immune system relies on T cells to fight infections. But T cells don't just show up and react—first, they train, get a game plan, and coordinate their defenses in lymphoid organs. Researchers have ...

Low testosterone may worsen the liver-damaging effects of high-fructose diets by altering gut microbes and metabolism, a new study in mice suggests.

Researchers have identified two gut bacteria that can produce serotonin, a key chemical that regulates bowel movements. In experiments with mice lacking serotonin, the microbes boosted serotonin ...

A new study shows that a high fat diet may weaken the gut barrier and allow bacteria to travel toward the brain through the vagus nerve.