Single-trial approvals are raising the bar on trial design and execution. The new paradigm is pushing sponsors to plan earlier, step up their data and risk‑based quality management and use modeling ...

As a result, the evolutionary pressures that once favored the appendix have largely disappeared. Meanwhile, the medical risks of keeping the appendix – most notably appendicitis – remain. Modern ...

Research is shaking up how we think about evolution, suggesting there's a level of predictability influenced by genes and genetic history.