Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.

A comprehensive review published in Spine Research synthesizes evidence on aggrecan, the core molecule responsible for hydration in spinal discs. The authors present the first comprehensive, 4-part ...

Post-traumatic osteoarthritis develops rapidly after joint injury, yet current treatments largely address symptoms rather ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

Neuromuscular diseases comprise a heterogeneous group of disorders characterized by progressive impairment of muscle function resulting from defects in ...

A first in-human, phase I trial examined feasibility as well as safety ...

Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells—also known as "zombie cells"—in diabetic kidney ...

Dry skin, or xeroderma and xerosis, occurs in 40% to 60% of all adults, especially in winter. It occurs in 70% to 99% of adults aged 60 years of age or older and increases with age.

Together, these findings indicate that astrocytes undergo profound sex- and region-specific adaptations to chronic ethanol, implicating extracellular matrix and glycosaminoglycan remodeling as key ...

The partnership combines RRG’s FDA-registered, CLIA-certified laboratory and industry-leading biologic products with ...