Senescence. It’s a beautiful-sounding word whose tones suggest it should be a perfume or an essential oil. But that’s not even close. Senescence is the loss of a cell’s power to divide and grow, thus ...

A team of researchers from the University of Aberdeen has uncovered, for the first time, how genes linked to autism and intellectual disability may influence early brain development. Their work helps ...

State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China Frontier Science Center for Rare Isotopes, School of ...

Growing from a single cell into a complex organism with specialized tissues and organs requires a complex and coordinated process. But the mechanical signals that guide tissue and organ ...

Recent works in mechanobiology have investigated overarching changes in cell behavior in response to extracellular matrix (ECM) stiffness. Nonetheless, little is known about how key metabolic pathways ...

The effects of ECM stiffness on LEC proliferation and migration were assessed using a tunable polyacrylamide hydrogel system. Differential gene expression in LECs on soft versus stiff substrates was ...

Uncontrolled bleeding during surgery remains one of the deadliest medical emergencies. Injuries to internal organs such as the liver or spleen are especially dangerous because bleeding is difficult to ...

This paper explores the role of extracellular vesicles in providing extracellular matrix signals for migration of vascular smooth muscle cells. The evidence, based on cell culture experiments and ...