Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.

Post-traumatic osteoarthritis develops rapidly after joint injury, yet current treatments largely address symptoms rather ...

Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells—also known as "zombie cells"—in diabetic kidney ...

A comprehensive review published in Spine Research synthesizes evidence on aggrecan, the core molecule responsible for hydration in spinal discs. The authors present the first comprehensive, 4-part ...

Dry skin, or xeroderma and xerosis, occurs in 40% to 60% of all adults, especially in winter. It occurs in 70% to 99% of adults aged 60 years of age or older and increases with age.

A first in-human, phase I trial examined feasibility as well as safety ...

Together, these findings indicate that astrocytes undergo profound sex- and region-specific adaptations to chronic ethanol, implicating extracellular matrix and glycosaminoglycan remodeling as key ...

A first-in-human trial shows the feasibility and safety of delivering placenta-derived stem cells during prenatal ...

Tezepelumab is associated with beneficial changes in nasal polyp gene expression in patients with chronic rhinosinusitis with ...

Within contemporary molecular biology, the regulation of tissue growth has emerged as a central theme linking developmental signaling, metabolic balance, and structural adaptation. Among the molecular ...

Repair of open neural tube defects, including myelomeningocele, in the fetus has been shown to improve postnatal outcomes by decreasing the severity of hydrocephalus and, consequentially, reducing the ...