Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

Post-traumatic osteoarthritis develops rapidly after joint injury, yet current treatments largely address symptoms rather ...

A comprehensive review published in Spine Research synthesizes evidence on aggrecan, the core molecule responsible for hydration in spinal discs. The authors present the first comprehensive, 4-part ...

A first in-human, phase I trial examined feasibility as well as safety ...

Together, these findings indicate that astrocytes undergo profound sex- and region-specific adaptations to chronic ethanol, implicating extracellular matrix and glycosaminoglycan remodeling as key ...

Neuromuscular diseases comprise a heterogeneous group of disorders characterized by progressive impairment of muscle function resulting from defects in ...

The partnership combines RRG’s FDA-registered, CLIA-certified laboratory and industry-leading biologic products with ...

Post-traumatic osteoarthritis often affects younger, active individuals and progresses quickly following ligament or cartilage injury. Chondrocytes, the sole cell type in articular cartilage, survive ...

A first-in-human trial shows the feasibility and safety of delivering placenta-derived stem cells during prenatal ...