Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

The first cell rejuvenation therapy is set to enter clinics, testing if aging cells can be reset to a younger, healthier ...

Underground environments like soil and aquifers teem with microbial life. These tiny microbes play a big role in cycling nutrients and breaking down or transforming pollutants. However, scientists ...

How does DNA structure itself from the very first moments of life? A team of researchers has just observed that DNA adopts a defined three-dimensional architecture much more rapidly than ...

Purdue University researcher Emily Dykhuizen explores how cancer takes advantage of the machinery that surrounds DNA, enabling some of its most pernicious powers, like the ability to evade the immune ...

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

With clinical data beginning to emerge, big pharma is signaling its belief that in vivo CAR generation is the next immunotherapy breakthrough.

When closely related species mate, their offspring sometimes survive but cannot reproduce. This pattern often affects males ...

Scientists have developed an AI system that analyzes complex gene-expression signatures to estimate the likelihood that a tumor will spread.

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve ...