How do GLP-1 agonists affect gene expression?

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...
Morning Overview on MSN

Scientists debut breakthrough molecule that sneaks DNA straight into living cells

A team led by Professor Shoichiro Asayama at Tokyo Metropolitan University has synthesized a charge-free molecule designed to sneak plasmid DNA into living cells via hydrogen bonding, dramatically ...
Nanowerk

Scientists develop a new method to decode how DNA 'switches' control gene activity

Less than 2% of the genome codes for proteins; the rest, once called 'junk DNA', contains regulatory elements. Researchers analyzed 10,000 to reveal how variants shape gene activity.
eLife

TAD boundary architecture and gene activity are uncoupled

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...