Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

In a new study, researchers compare the transcriptomic profiles of recently reported human embryo stage 8-cell-like cells with human embryos The onset of embryo-specific gene transcription, also known ...

A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...