Read more about Nanoparticle and AI-driven vaccines target broad protection against emerging threats on Devdiscourse ...

In summer 2025, the SARS-CoV-2 JN.1 sublineage became dominant with more resistant variants, such as XFG, LP.8.1, and NB.1.8.1. COVID-19 mRNA boosters were therefore updated for the 2025–2026 season ...

SLAMF6 is an immune cell receptor whose function was not clear. Does it activate or inhibit cells? The results so far have been contradictory. Now, scientists at the Institut de Recherches Cliniques ...

撰文丨王聪编辑丨王多鱼排版丨水成文全世界有数十亿人因为文化或医疗目的而禁食（Fasting），近年来，热量限制（CR）和间歇性禁食（IF）等禁食方案被用作减肥方式而在世界范围内愈发流行，不少人甚至将其奉为健康箴言。此外，越来越多研究表明，禁食在广泛的 ...

引言皮肤，作为人体抵御外界环境挑战的第一道防线，其功能远不止于简单的物理屏障。长久以来，免疫学界一直存在一个引人深思的谜题：当我们的皮肤局部遭遇微小的感染或损伤时，身体是如何迅速将这一局部的“危机信号”转化为长效、系统性的全身抗体免疫记忆的？3月4日 ...

在感染或紫外线照射后，角质形成细胞内通过未折叠蛋白反应-SREBF 通路介导的甲羟戊酸通路激活，导致 FPP 积累，从而放大引流淋巴结中的生发中心（GC）反应。

EAE-induced neuroinflammation. Using immuohistochemistry, flow cytometry, and single-cell RNAseq of doublets to interrogate cell-cell interactions, the authors provide solid evidence that macrophages, ...

在这里，研究人员在人类和小鼠模型中显示，间歇性禁食通过加速抗体衰减损害体液免疫记忆。禁食选择性地消耗小鼠的LLPCs，而不消耗MBCs。从机理上讲，这种效应是由细胞外β-羟基丁酸盐 (禁食时产生的一种酮体)的增加介导的，它通过浆细胞上的羟基羧酸受体2 (HCAR2)发挥作用。

In recent decades, acupuncture has attracted extensive research spanning an astonishingly wide array of medical conditions, from chronic pain and neurological disorders to infectious diseases and ...