Neurogenic bladder dysfunction, such as detrusor muscle hyperactivity and dyssynergia with the external urethral sphincter (EUS), are common long-term consequences affecting the wellbeing of patients ...

Researchers have shown how an experimental drug might restore the function of nerves damaged in spinal cord injuries by preventing short circuits caused when tiny "potassium channels" in the fibers ...

Timed release of therapeutic molecules from a soft nanofiber-hydrogel implant supports nerve regrowth and circuit repair after spinal injury, restoring movement and bladder control in preclinical ...

Researchers are exploring a new therapy using stem cells to treat spinal cord injuries within the first 14 to 30 days of injury. The therapy uses a population of cells derived from human embryonic ...

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease. An intervention, ...

The lumbar plexus is a nerve plexus (a network of intersecting nerves) in the body’s lumbar region. It is formed by the ventral branches of the first to the fourth upper lumbar nerves (L1-L4), with ...

When the spinal cord is injured, the damaged nerve fibers--called axons--are normally incapable of regrowth, leading to permanent loss of function. Considerable research has been done to find ways to ...

Neurological functions following spinal cord injury have generally been assessed using the American Spinal Injury Association (ASIA) impairment scale. However, the scale primarily evaluates motor ...

Injury to the spinal cord triggers a cascade of biological events that unfold within seconds and that proceed for months or even years. The events affect three major bodily systems: the nervous system ...