来自澳大利亚彼得-麦卡伦癌症中心等机构的科学家们通过利用黑腹果蝇(Drosophila melanogaster)作为研究癌症恶病质的模型，结果发现，肿瘤会分泌一种名为Mmp1的酶类，该酶主要负责分解脂肪和肌肉。 2021年9月4日 讯 /生物谷BIOON/ --恶病质（Cachexia）是一种肿瘤诱发 ...

本研究针对非小细胞肺癌(NSCLC)高转移特性导致的临床治疗困境，通过体内外实验首次揭示溶瘤疱疹病毒OH2通过其皮层蛋白UL41 ...

Matrix metalloproteinases (MMPs) have a key role in the invasion and metastasis of a variety of tumors. Researchers have investigated whether epithelial (tumor-cell-derived) and stromal (host-derived) ...

为探究 MMP-2、MMP-9 和 MMP-13 在脊柱感染致椎间盘破坏中的作用及与临床数据的关联，宁夏医科大学总医院研究人员开展研究。结果显示，三者在感染患者椎间盘组织中表达升高，且与临床指标相关。该研究为脊柱感染的诊疗提供新依据。 在人体的 “顶梁柱 ...

Find a way to control cell movement, and you've got an excellent weapon in the fights against tumorigenesis and inflammation, an excellent clue as to how organisms develop, and an excellent tool in ...

Purpose: To determine changes in production of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in the ciliary body, the trabecular meshwork and the retinal ...

Matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, are capable of degrading almost all protein components of the extracellular matrix (ECM). MMPs have garnered attention as ...

Lymphangioleiomyomatosis, a rare lung disease typically affecting women of reproductive age, is characterized by an abnormal proliferation of smooth-muscle cells and the progressive loss of pulmonary ...