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MacMillan课题组JACS:醇的自由基脱氧胺化反应构建C(sp³)-N键
近日,2021年诺贝尔化学奖得主、美国普林斯顿大学默克催化中心(Merck Center for Catalysis at Princeton University)David W. C. MacMillan课题组发展了一种铜金属光氧化还原策略,实现了醇与N-亲核试剂的开壳脱氧偶联,构建了C(sp3)-N键。利用此策略可以实现具有高价值的药物 ...
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