A new study led by researchers from VIB and KU Leuven shows that immune cells called microglia can actively promote the formation of plaques in Alzheimer's disease, challenging the long-standing view ...

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder ...

Loss and dysfunction of synapses have been linked to age-related cognitive decline and observed in Alzheimer's and other ...

Researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study also integrates drug databases with real ...

Scientists broadly agree that both apolipoprotein E and microglia are necessary ingredients for amyloidosis. In mice devoid of ApoE, or of their microglia, scant plaques form. Now, a sweeping study ...

Until now, conventional 3D cell cultures have often been either too rigid or too unstable to realistically reproduce the complex interactions between brain cells. Researchers at Kiel University (CAU) ...

A Dartmouth study published in Nature Communications reveals that immune cells in the brain use a surprising two-step process to power their search-and-destroy missions. When immune cells rush to ...

When young donor myeloid cells are transplanted into aging mouse brains, they quickly adopt aging phenotypes. In contrast, old myeloid cells transplanted in young brains take on a more youthful aspect ...

Researchers from the Alzheimer's Center at Temple (ACT) provide new insights into how microglia, the brain's immune cells, exhibit an apparent dual function with the ability to both increase and ...

The new generation of Alzheimer's disease drugs - the first proven to change the course of the disease - typically extend independent living for patients by 10 months. Called monoclonal antibodies, ...