Chronic disease research increasingly points to the centrality of metabolic remodeling and mitochondrial dysfunction in dictating disease onset, severity, ...

You will be redirected to our submission process. This Research Topic is part of the Mechanisms and Novel Therapeutic Targets and Approaches for Mitochondrial Dysfunction in Neurological and ...

Advances in reproductive biology are revealing that ovarian aging is not only a matter of declining egg numbers but also a ...

For patients with cancer and brain metastases (BM) and type 2 diabetes (T2D), glucagon-like peptide-1 receptor agonist (GLP-1 ...

Many people chalk up persistent fatigue and constant sugar cravings to a “slow metabolism,” but according to physician Dr. Phuong Vo, what’s actually happening beneath the surface is far more complex.

CD4+ T cells, long regarded as supporting actors in cancer immunity, are emerging as central regulators of tumor control and ...

Northwestern Medicine scientists led by Joseph Bass, MD, Ph.D., the Charles F. Kettering Professor of Endocrinology and ...

Don’t get old before your time. A number of very common everyday habits can accelerate biological aging, putting extra stress on your cells and organs and making yourself more susceptible to certain ...

The findings of this cohort study suggest that glucagon-like peptide–1 receptor agonist (GLP-1 RA) use was associated with significant reduction in all-cause mortality among patients with cancer with ...

Geroscience examines the underlying biology of aging to delay chronic diseases and extend the healthy years of human life.

We’re learning that frailty can quietly arrive decades before old age, with some people in their 30s or 40s unknowingly in a pre-frail state. There are surprising ways to stay strong – and it’s not al ...

The ovaries age faster than other organs, decreasing fertility over time. This article explores drivers of ovarian aging and ...