New research suggests the erectile dysfunction drug Viagra could help treat a devastating neurological disorder that primarily strikes young children — most of whom die before the age of three. The ...

The mitochondria, perhaps better known as the powerhouses of cells, are emerging as a possible factor in the pains of aging.

For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...

Don’t get old before your time. A number of very common everyday habits can accelerate biological aging, putting extra stress ...

Chronic disease research increasingly points to the centrality of metabolic remodeling and mitochondrial dysfunction in dictating disease onset, severity, ...

Many people chalk up persistent fatigue and constant sugar cravings to a “slow metabolism,” but according to physician Dr. Phuong Vo, what’s actually happening beneath the surface is far more complex.

Coenzyme A, a molecule derived from vitamin B5, is vital for metabolism throughout the body. Scientists discovered that most of it resides inside mitochondria, yet how it reached these cellular ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to ...

Researchers create a massive single-cell atlas of the aging mouse brain, revealing how epigenetic changes and "jumping genes" drive neurodegeneration.

You will be redirected to our submission process. This Research Topic is part of the Mechanisms and Novel Therapeutic Targets and Approaches for Mitochondrial Dysfunction in Neurological and ...

The findings of this cohort study suggest that glucagon-like peptide–1 receptor agonist (GLP-1 RA) use was associated with significant reduction in all-cause mortality among patients with cancer with ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...