Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

Michael Rout has spent decades studying the molecular machinery that controls all traffic in and out of the cell’s nucleus. His research could lead to new treatments for cancer and viral diseases.

More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study ...

Michael Rout, the George and Ruby deStevens Professor and head of the Laboratory of Cellular and Structural Biology at Rockefeller University, has spent his career parsing the inner workings of the ...

Every second, hundreds to thousands of molecules move through thousands of nuclear pores in each of your cells. A new high-definition view reveals the machine in action.

Researchers have found evidence of nuclear metabolic enzymes for the first time, contributing to our understanding of cancer ...

More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study ...

In rare genetic ALS tied to VCP mutations, an overactive “cleanup” system may damage nerve cells. The study links VCP overactivity to nuclear pore disruption and abnormal TDP-43 location in cells.

Nuclear pore complexes are more dynamic than previously thought, reshaping our understanding of a vital transport process in cells. An international study led by the University of Basel (Switzerland) ...