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基于果胶的纳米递送平台在靶向性与载药量优化平衡中实现肝癌高效 ...
研究人员针对多糖基纳米药物在多功能性平衡调控方面的空白,开发了氧化半乳糖修饰的果胶纳米前药平台(OP-DOX NPs),通过调控氧化度优化主动靶向与载药量的平衡。筛选出的OP6-DOX NPs在肝癌治疗中实现86.8%的肿瘤抑制率,有效诱导TAMs从M2向M1极化并招募NK细胞 ...
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