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猪源β防御素5的全化学合成及其对革兰氏阳性菌与阴性菌的抗菌特性 ...
面对日益严重的抗菌素耐药性(AMR)威胁,研究人员开展了以宿主防御肽(HDP)猪源β防御素5(pBD-5)为主题的研究。他们通过正交保护策略合成了具有三对二硫键的pBD-5,评估了其对大肠杆菌和表皮葡萄球菌的剂量依赖性抗菌活性、结构稳定性及对猪红细胞的 ...
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