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具有内源性活性氧(ROS)生成能力的抗菌肽微针,用于治疗厌氧性 ...
厌氧菌感染因代谢缓慢易耐药且易引发多菌种感染,本研究利用诱导厌氧菌生成ROS的抗菌肽WRK(4 μg mL?1 抑制游离菌,64 μg mL?1 破坏生物膜),通过微针递送至真皮层治疗痤疮丙酸杆菌感染,动物实验证实其抗炎效果优于克林霉素凝胶。 摘要 由厌氧细菌引起的 ...
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