Avidin‑PEG‑RGD是一种通过聚乙二醇（PEG）链连接并修饰RGD肽（Arg-Gly-Asp，精氨酸-甘氨酸-天冬氨酸三肽）的亲和素衍生物。该分子可作为药物递送系统的功能化支架，兼具亲和素的生物分子连接能力、PEG链的柔性和水溶性以及RGD肽的结合特性。 其主要组成包括 ...

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical ...

Scientists have developed Evo 2, a powerful AI model that can analyze and generate DNA sequences across all domains of life.

A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising ...

在生命科学研究中，RNA的提取与纯化是基因表达分析、转录组研究和功能基因组学等实验的基础环节。高质量的总RNA不仅决定了后续实验的成功率，更直接影响数据的准确性和可靠性。面对市场上琳琅满目的RNA提取试剂盒，如何选择一款性能稳定、操作简便且 ...

Scientists have identified an RNA-based sperm aging clock driven by rsRNA length changes, which may help assess paternal ...

The team will adopt a dual WES-WTS approach for more detailed tumour profiling. Lucence, Diagnostics Development Hub hosted ...

For decades, scientists have recognized that human immunodeficiency virus (HIV) is a formidable viral pathogen. After years ...

为了让微小的RNA分子在冷冻电镜下“显形”，一种直观的思路是人为地给它们“增重”。在此前的研究中，人们尝试过将目标RNA（客体）共价连接到已知结构的巨型RNA分子（主体）上，例如使用长达250到400个核苷酸的I型或II型自剪接内含子作为支架。这种方法虽然取得了一定成效，但庞大的主体结构使得整个复合物变得过于臃肿，目标客体RNA在整个颗粒中只占据极小的比例，导致计算资源的大量消耗，且往往难以获得客 ...

UK agbiotech Tropic raises $105m to scale gene-edited non-browning and extended shelf-life bananas, and advance TR4-resistant varieties.

Messenger RNA therapy restores sperm production, enabling healthy offspring in a mouse model of genetic male infertilityResearchers in Japan have demonstrated that targeted delivery of messenger ...