这篇综述系统阐述了选择素(Selectins)在动脉粥样硬化(AS)中的多维度作用机制,突破性地将其从传统黏附分子重新定义为 ...
Figure 2: The effect of E-selectin on HSC turnover is mediated by the bone marrow microenvironment. Figure 3: E-selectin–expressing endothelial cells are enriched in the endosteal region. Figure 4: ...
Memory T lymphocytes extravasate at sites of inflammation, but the mechanisms employed by these cells to initiate contact and tethering with endothelium are incompletely understood. An important part ...
Dynamics of growth of transplantable sarcoma 45 (S45) in injection of autologous and allogenic serum. Dynamics of IGF-I, IGF-II and TGF-β1 in lung and liver in the early stages of metastasis in ...
Selectins are required for the trafficking of innate immune system cells, T lymphocytes and platelets. The absence of selectins or their ligands has severe health ...
In a surprising discovery, a ‘sticky molecule’ that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new ...
This image shows a metastatic melanoma tumor in a lung. Blood vessels at the tumor site (yellow) express a protein called P-selectin. Blood vessels not expressing P-selectin are green. Nanoparticles ...
A Princeton-led team of researchers has discovered a factor that promotes the spread of cancers to bone, opening the way toward treatments that could mitigate cancer’s ability to colonize bone. The ...
In a surprising discovery, a "sticky molecule" that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new ...
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