Figure 2: The effect of E-selectin on HSC turnover is mediated by the bone marrow microenvironment. Figure 3: E-selectin–expressing endothelial cells are enriched in the endosteal region. Figure 4: ...
Selectins are required for the trafficking of innate immune system cells, T lymphocytes and platelets. The absence of selectins or their ligands has severe health consequences, with recurrent ...
This image shows a metastatic melanoma tumor in a lung. Blood vessels at the tumor site (yellow) express a protein called P-selectin. Blood vessels not expressing P-selectin are green. Nanoparticles ...
Memory T lymphocytes extravasate at sites of inflammation, but the mechanisms employed by these cells to initiate contact and tethering with endothelium are incompletely understood. An important part ...
Dynamics of growth of transplantable sarcoma 45 (S45) in injection of autologous and allogenic serum. Dynamics of IGF-I, IGF-II and TGF-β1 in lung and liver in the early stages of metastasis in ...
When cancer metastasizes, cells break off from the primary tumor, travel through the lymphatic or circulatory system, and then invade other tissue. Now researchers have found a protein that allows ...
An open-label expanded-access study to evaluate the safety, tolerability, and pharmacokinetics of trifluridine/tipiracil in patients with advanced solid tumors and hepatic impairment. This is an ASCO ...
A Princeton-led team of researchers has discovered a factor that promotes the spread of cancers to bone, opening the way toward treatments that could mitigate cancer’s ability to colonize bone. The ...
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