Neurodegenerative disease profoundly affects structures and pathways responsible for memory, cognition, and higher-order ...

The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...

ABSTRACT: Psychiatric and neurological disorders often exhibit overlapping symptomatology and shared neurobiological mechanisms, yet pharmacological treatments are typically developed and administered ...

Summary: New research has overturned a long-held belief in neuroscience by showing that the brain uses separate synaptic transmission sites for spontaneous and evoked signaling. Traditionally thought ...

Your brain doesn t just send messages through one universal route it uses separate pathways for spontaneous activity and signals linked to learning. These findings overturn a major neuroscience ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...

Abstract: NEURON simulations for mossy fiber boutons show that conductivity changes in one bouton can induce resting membrane potential changes in nearby boutons, altering the pre-synaptic Calcium ...

Observe the intricate process of synaptic transmission, showcasing how neurotransmitters are released and their essential role in communication within the nervous system. 3D animation. Royalty-free ...

This fundamental work substantially advances our understanding of the role of calcium-binding proteins 1 and 2 (CaBP1 and CaBP2) for generating sustained calcium currents in mouse inner hair cells and ...

A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...

The Department of Energy (DOE) has awarded capacity contracts of up to $1.5 billion to four major transmission lines under its Transmission Facilitation Program (TFP) to aid the transfer of 7.1 GW of ...