这篇研究揭示了外源性三磷酸腺苷(ATP)通过重编程代谢组学激活三羧酸循环(TCA cycle),促进活性氧(ROS)生成并增强膜通透性,从而逆转碳青霉烯耐药鲍曼不动杆菌(CRAB)对美罗培南的耐药性。研究不仅阐明了ATP通过TCA循环-电子传递链-ROS轴增强抗生素效能 ...
Detachment of epithelial cells from the extracellular matrix (ECM) can induce profound changes in cellular metabolism, including decreased glucose uptake and ATP production. However, the mechanism by ...
If you took biochemistry classes, chances are good you remember memorizing the Krebs cycle, a well-known metabolic pathway in which sugars are converted through a series of steps to generate ATP, a ...