本研究针对变应性鼻炎(AR)治疗瓶颈，通过整合生物informatics分析、网络药理学与分子对接技术，首次系统阐明紫草素通过多靶点调控TNF通路（涉及TNF、TNFAIP3、NFKB1等关键靶点）抑制IL-13诱导的鼻上皮细胞损伤的作用机制，为AR精准治疗提供新策略。 随着全球范围 ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the ...

A study published in The EMBO Journal opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor-α (TNF ...

The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients. New research led by ...

The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients. Subscribe to our ...