Transcription factors are proteins that bind to DNA to regulate gene expression via transcription: the process by which the genetic code generates mRNAs or small RNAs. Transcription factors operate by ...

H2Bub1 is a master epigenetic regulator that orchestrates the elongation-to-termination transition of sense transcription in S. pombe by directly modulating a Cdk9-PP1 switch mechanism. Loss of H2Bub1 ...