In theory, Rap30 could replace the linker histones in the promoter region, maintaining some of the architecture of the promoter, which could be important for stable preinitiation complex formation.

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

A secondary stress signaling pathway in the response to optic axon injury is an unexpectedly strong contributor to both neurodegeneration and axon regenerative potential.

A conserved glucagon signaling pathway links high-fat diet-induced metabolic imbalance to cardiac arrhythmia through hormone-producing cells and heart-innervating neurons that regulate rhythmicity.

By combining high-resolution genomic data with AI, researchers are uncovering the regulatory logic plants use to sense and survive environmental stress.

From left to right: Dr. Raymond Deshaies, Dr. Lyn Jones, and Dr. Juri Rappsilber, newly appointed members of Proxima's Scientific Advisory Board.