A new study led by researchers from VIB and KU Leuven shows that immune cells called microglia can actively promote the formation of plaques in Alzheimer's disease, challenging the long-standing view ...
Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the ...
Microglia (immune cells) and the RANK protein are essential for triggering puberty and maintaining fertility in the brain.
Scientists have spent decades trying to understand exactly how Alzheimer’s begins and why it gets worse over time. A major feature of the disease is the buildup of sticky protein clumps in the brain ...
Engineered immune cells targeted and reduced the toxic protein plaques that drive Alzheimer’s disease in a recent study.
The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a ...
Microglia cells (green) interacting with GnHR neurons (red) in mice hypothalamus from both the control group (top) and the group with supressed Rank protein (bottom). Without Rank, microglia cells are ...
When the digestive system fails to absorb fructose, the lingering sugar disrupts the gut microbiome. A recent study reveals this bacterial shift sparks low-grade, body-wide inflammation that can alter ...
The new generation of Alzheimer's disease drugs—the first proven to change the course of the disease—typically extend independent living for patients by 10 months. Called monoclonal antibodies, they ...
Scientists have developed a promising new approach to treating Alzheimer’s disease by turning ordinary brain cells into powerful plaque-clearing machines. Instead of requiring frequent antibody ...