The FDA has published new guidance aimed at reducing or stopping toxicity studies of monoclonal antibody-based drugs in non-human primates (NHPs), in the latest stage of an ongoing effort to reduce ...

Dose-limiting toxicity affects 31–34% of patients treated with 5-fluorouracil (5-FU). Dihydropyrimidine dehydrogenase (DPD) is a key enzyme in the detoxification of 5-FU; patients with a complete or ...

Scientists and regulators have long acknowledged the weaknesses in traditional methods used to identify drugs that may harm the central nervous system. One in four safety-related failures arise from ...

If you click on links we provide, we may receive compensation. It's on sale today at Amazon Maggie Horton is a shopping writer for PEOPLE who regularly covers buzzy kitchen products, newly released ...