Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the ...
Alector, Inc. (ALEC) pivots to its Alector Brain Carrier (ABC) platform, focusing on enhanced blood-brain barrier delivery ...
Neuropathic pain is a devastating type of pain that significantly reduces the quality of life of affected people.
LDC7559（AbMole，M13554）是一种泛凋亡（PANoptosis）相关分子消皮素 D (GSDMD) 的抑制剂，最初通过从化合物库中筛选抑制佛波酯（Phorbol 12-myristate 13-acetate，PMA）诱导的中性粒细胞胞外杀菌网络（NETosis）而被发现，它在PMA诱导的NETosis中IC50约为5.6 μM，在胆固醇晶体诱导的NETosis中IC50约为300 ...
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