Preosteoclasts give rise to bone-resorbing osteoclasts, which are crucial for skeletal homeostasis. A study now shows that preosteoclasts also contribute to bone formation by releasing ...

Periosteal distraction osteogenesis is an innovative technique that leverages the intrinsic osteogenic potential of the periosteum to stimulate new bone formation. By gradually elevating this highly ...

For decades, the rare bone condition osteogenesis imperfecta has been diagnosed on a spectrum, from mild to lethal. New research by Nemours Children's Health physicians suggests that many babies whose ...

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...

Osteogenesis imperfecta is a heritable disorder that causes bone fragility. Mutations in type I collagen result in autosomal dominant osteogenesis imperfecta, whereas mutations in either of two ...

A new study led by Baylor College of Medicine identifies an underlying mechanism of pathogenesis for osteogenesis imperfecta (OI) in human bone. The report, published in the Journal of Clinical ...

Please provide your email address to receive an email when new articles are posted on . The classification system associated with prenatally diagnosed osteogenesis imperfecta may be outdated. Modern ...