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生物通
6 个月
综述:多核糖体分选调控mRNA定位与蛋白质命运
这篇综述颠覆性地揭示了新生蛋白质(nascent protein)在mRNA定位中的核心作用,提出多核糖体(polysome)通过共翻译相互作用主动调控自身运输的新范式。文章以翻译工厂(translation factories)和中心体mRNA(centrosomal mRNAs)为例,阐明了共翻译分选(cotranslational ...
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