CAIRO, March 11 (Xinhua) -- The warfare sparked by U.S.-Israeli strikes on Iran entered its 12th day on Wednesday, with more than a dozen nations affected so far and shockwaves felt across the globe.

Be/feel out of sorts 身体不舒服 心情不太好 Episode 191212 / 12 Dec 2019 Learn a useful expression to say you’re not feeling too bad but not very well in English ...

实际上，近25年来已有11种小分子药物被报告能够重新激活突变型p53功能。其中，PRIMA 首先被报告通过与DNA结合区半胱氨酸残基结合，可恢复突变型p53的结构、转录活性和细胞生长抑制功能。随后，PRIMA甲基化衍生物APR-246被研发，并进入一期和二期临床试验，但是三期临床试验失败。