Researchers develop 4e, a psilocin derivative that provides sustained serotonin activity without the hallucinogenic effects of magic mushrooms.

Researchers found that psilocybin and MDMA may alleviate PTSD symptoms by promoting myelin remodeling in the brain. In rat models, psychedelic treatment triggered oligodendrocyte-driven myelin repair ...

Post-traumatic stress disorder (PTSD) is not only characterized by strongly encoded traumatic memories, but also by disrupted coordination across brain networks. New research shows that treatment with ...

New research reveals that psilocybin and MDMA promote long-term PTSD recovery by physically remodeling myelin insulation in ...

Post-traumatic stress disorder (PTSD) is not only characterized by strongly encoded traumatic memories, but also by disrupted coordination across brain networks. New research shows that treatment with ...

Professor of Pathology, Lee J. Martin, discusses the prevalence and treatment challenges associated with hypoxic-ischemic encephalopathy (HIE) ...

This article and associated images are based on a poster originally authored by Sophie O’Neil, Kyle Thompson, Rita Pereira, Emily Russell and Stuart McElroy and presented at ELRIG Drug Discovery 2025 ...

Panic Disorder (PD) is a prevalent psychiatric condition characterized by recurrent episodes of acute severe anxiety. These episodes frequently present with symptoms that overlap with those of ...

Researchers at Mount Sinai have mapped how the 5-HT1A serotonin receptor controls brain signalling – finding a hidden lipid ‘co-pilot’ that could lead to the development of more targeted ...

Provided herein are novel substituted lactams as 5-HT1A agonists, pharmaceutical compositions, use of such compounds in treating neuropsychiatric diseases and processes for preparing such compounds.