Group A Streptococcus (GAS) causes extensive global morbidity and rising rates of invasive disease, for which clinical outcomes remain poor despite antibiotic treatment of susceptible strains. This ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

This article was produced in partnership with Regeneron by Scientific American Custom Media, a division separate from the magazine’s board of editors. In the long-running quest to improve on ...

Within the tumor microenvironment (TME) of solid malignancies, tumor-infiltrating antibodies, have been identified as significant modulators of tumor progression and immune response.

Background: Fibrosis is a hallmark of heart disease, yet direct antifibrotic therapies remain limited. We identified ANTXR1, a master regulator of fibrosis, overexpressed in diseased cardiac tissue ...

This technical animation shows the setup and function of the Digital Matrix LED headlights in the Audi Q3 SUV. Pete Hegseth fires Navy chief of staff Jon Harrison McDonald's Halloween Boo Buckets Are ...

In less than a decade, bispecific antibodies have gone from scientific curiosity to frontline cancer therapeutics. These engineered proteins, capable of binding to two or more targets simultaneously, ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.