Scientists at Washington University in St. Louis have engineered brain cells to hunt and destroy amyloid plaques, cutting toxic buildup by roughly half in aged mice with advanced Alzheimer’s-like ...

A single treatment of viral vector-delivered CAR-A construct in mice with existing plaque saturation cut the amount of amyloid plaques in half.

Researchers engineer CAR-astrocytes to target and remove amyloid plaques in Alzheimer’s, showing a 50% reduction in brain ...

WashU Medicine researchers designed a cellular immunotherapy that turns astrocytes (green), a type of cell in the brain, into super cleaners that sweep away Alzheimer’s-related proteins. With this new ...

A new study reveals that astrocytes, once dismissed as mere support cells, play a central role in fear memory.

Scientists have identified prematurely aged astrocytes in the brains of Alzheimer’s patients, particularly those with the APOE4 risk gene. Their findings suggest that cellular senescence in these ...

Tau proteins play an important role in our normal brain function, mainly by helping to stabilize neurons in the brain. But in Alzheimer’s disease, tau proteins can misfold and tangle inside neurons.

When we learn a new motor skill—whether mastering a piano passage or refining balance while walking—the brain must reorganize the circuits that control movement. For decades, this process of synaptic ...

Human spinal cord organoids have been used to model different types of spinal cord injuries and test a promising new regenerative therapy.

In a recent study published in Neuropsychopharmacology, researchers from the University of Technology Sydney (UTS) found that inflammation in a key decision-making region of the brain led to more ...

Picture a star-shaped cell in the brain, stretching its spindly arms out to cradle the neurons around it. That's an astrocyte, and for a long time, scientists thought its job was caretaking the brain, ...