Studying the minds of octogenarians with surprising cognitive resilience shows how it's possible to maintain a youthful brain well into old age.
Astrocytes in the cerebellum trigger a shift in GABA signaling during late adolescence, enabling adult-level motor coordination.
A new study reveals that astrocytes—star-shaped support cells traditionally viewed as passive partners of neurons—play a ...
Edited by Jeremy Nathans, Johns Hopkins University School of Medicine, Baltimore, MD; received October 24, 2024; accepted June 2, 2025 ...
A new study reveals that astrocytes—star-shaped support cells traditionally viewed as passive partners of neurons—play a previously underappreciated role in the maturation of coordinated movement. A ...
Scientists at Washington University in St. Louis have engineered brain cells to hunt and destroy amyloid plaques, cutting toxic buildup by roughly half in aged mice with advanced Alzheimer’s-like ...
A single treatment of viral vector-delivered CAR-A construct in mice with existing plaque saturation cut the amount of amyloid plaques in half.
Researchers engineer CAR-astrocytes to target and remove amyloid plaques in Alzheimer’s, showing a 50% reduction in brain ...
The new generation of Alzheimer's disease drugs—the first proven to change the course of the disease—typically extend ...
A new study reveals that astrocytes, once dismissed as mere support cells, play a central role in fear memory.
Scientists have identified prematurely aged astrocytes in the brains of Alzheimer’s patients, particularly those with the APOE4 risk gene. Their findings suggest that cellular senescence in these ...
For some time, the field of neuroscience has been predominantly "neurocentric," viewing neurons as the primary agents of information processing while ...