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Nature:肠→脑"失联",或是记忆衰退元凶 | 热心肠日报
① 研究背景与设计:针对衰老伴随认知衰退的机制问题,结合宏基因组学、活体钙成像及小鼠行为学模型等方法,探究肠道微生物组老化对脑功能的影响机制。② 核心发现与意义:衰老相关的肠道特定共生菌及其代谢物积累,通过驱动外周髓系细胞炎症,削弱 ...
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