Delve into the field of pulmonary hypertension as GSK places a $950M bet on 35Pharma's candidate HS235 following the footsteps of Winrevair.

A team of researchers at RPI, in collaboration with the University of South Florida, University of North Carolina, and The Neural Stem Cell Institute, have made a discovery that opens the door to new ...

New research highlights amivantamab's potential in enhancing treatment outcomes for RAS/BRAF wild-type metastatic colorectal cancer, addressing resistance to standard therapies. In the evolving ...

Benign prostatic hyperplasia (BPH) is a prevalent condition characterized by nonmalignant proliferation of epithelial and stromal components in the prostate, frequently resulting in lower urinary ...

The canonical Wnt signaling pathway is activated when a Wnt protein binds to a Frizzled receptor and its co-receptor (Figure 1A; Nusse and Clevers, 2017). This interaction results in the recruitment ...

P. J. Boersema, R. Raijmakers, S. Lemeer, S. Mohammed, A. J. R. Heck, Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics. Nat. Protoc. 4 ...

The Hippo/yes-associated protein (YAP) signaling is an evolutionarily conserved regulator in organ size control, which plays pivotal roles in cell proliferation, differentiation, apoptosis, and tissue ...

1 Graduate School, Youjiang Medical College for Nationalities, Baise, China. 2 Department of Otorhinolaryngology—Head and Neck Surgery, Southwest Hospital Affiliated to Youjiang Medical University for ...

Microglia, the resident immune cells of the central nervous system (CNS), are highly dynamic and play critical roles in maintaining CNS homeostasis. Under normal conditions, microglia continuously ...