A recent review identifies interleukin-36 (IL-36) as a transformative driver of vascular inflammation, revealing that serum concentrations in patients with coronary artery disease (CAD) are ...

Growing neurons rely on chemical cues to find their targets, but new research shows that the brain’s physical properties help ...

Molecularly targeted therapies are increasingly relevant in clinical oncology, as they enable the selective modulation of specific biologic targets—such as enzymes or receptors—by inhibiting or ...

Mice were treated by 2.5% dextran sulfate sodium (DSS) for 7 days to established acute experimental colitis. Small intestinal tissues were collected at different time points in the process of ...

On the occasion of Rare Disease Day, the Biofisika Institute (CSIC, EHU) presents the progress of a project aimed at understanding the molecular origin of CTNNB1 neurodevelopmental syndrome, a rare ...

The genetic network of BTB zinc finger transcription factors and Eip93F is crucial for Kenyon cell identity regulation and neuronal function acquisition in the construction of Drosophila mushroom ...

Under states of cellular stress or inflammatory signaling, investigations indicate that IRR expression may increase, allowing selective ligands such as ARA-290 to initiate downstream signaling.

Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more effectively. The new approach could be a way to deliver treatment directly to tumors ...