Inside each of your cells lies a nucleus, its master command center. Protected inside each nucleus are your chromosomes, ...

The origin of the nucleus remains hotly debated among scientists, but new imaging and genomic data are shedding light on this billion-year-old mystery.

Michael Rout has spent decades studying the molecular machinery that controls all traffic in and out of the cell’s nucleus. His research could lead to new treatments for cancer and viral diseases.

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

Every second, hundreds to thousands of molecules move through thousands of nuclear pores in each of your cells. A new high-definition view reveals the machine in action.

A mutation in the TDP-43 protein reduces the viability of motor neurons without triggering protein clumps, researchers found.

A giant DNA virus pulled from a Japanese freshwater pond is forcing scientists to rethink how complex cells first acquired their defining feature: the nucleus. Named ushikuvirus, the newly ...

In A Nutshell Researchers at Tokyo University of Science developed a method to create fluorescent, irregularly shaped ...

Antisense oligonucleotides (ASOs), used to treat genetic diseases, can affect how cells repair damage to their DNA. This is ...

Michael Rout, the George and Ruby deStevens Professor and head of the Laboratory of Cellular and Structural Biology at Rockefeller University, has spent his career parsing the inner workings of the ...