In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

The origin of the nucleus remains hotly debated among scientists, but new imaging and genomic data are shedding light on this billion-year-old mystery.

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

The image shows the cross section mutant brown adipose tissue section with enlarged lipid droplets (yellow) and nucleus (blue) being impinged by multiple mitochondria (red). Mitochondria are ...

When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This ...

The investigations of KIT researchers have shown that biomolecular condensates enable fast yet reliable activation of the right genes. “Biomolecular condensates are tiny drops that form in specific ...